β-adrenergic receptor Selective Inhibitors | Agonists | Antagonists

Cat.nr.	Productnaam	Informatie	Selectief / Pan	IC50 / Ki
S4085	Levobetaxolol HCl	Levobetaxolol exhibits a higher affinity at cloned human β1 and β2 receptors with K_i value of 0.76 nM and 32.6 nM, respectively.	Selective	β2-adrenergic receptor, Ki: 32.6 nM; β1-adrenergic receptor, Ki: 0.76 nM; β2-adrenergic receptor, Ki: 32.6 nM; β1-adrenergic receptor, Ki: 0.76 nM
S1549	Nebivolol	Nebivolol selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM.	Selective	β1-adrenoceptor, IC50: 0.8 nM
S4123	Timolol Maleate	Timolol Maleate is a non-selective, beta-adrenergic receptor antagonist for β1/β2 with K_i of 1.97 nM/2.0 nM.	Selective	β2-adrenergic receptor, Ki: 2.0 nM; β1-adrenergic receptor, Ki: 1.97 nM
S2507	Salbutamol Sulfate	Salbutamol Sulfate is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM.	Selective	β2-adrenergic receptor, IC50: 8930 nM; β2-adrenergic receptor, IC50: 8.93 nM
S4076	Propranolol HCl	Propranolol HCl is a competitive non-selective beta-adrenergic receptors inhibitor with IC50 of 12 nM.	Selective	β-adrenergic receptor, IC50: 12 nM
S4009	Mirabegron	Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.	Selective	β3-adrenoceptor, EC50: 22.4 nM
S3083	Indacaterol Maleate	Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pK_i of 7.36.	Selective	β-adrenoceptor, pKi: 7.36
S4127	Terbutaline Sulfate	Terbutaline Sulfate is a selective β2-adrenergic receptor agonist with IC50 of 53 nM.	Selective	β2-adrenergic receptor, IC50: 53 nM
S1827	Betaxolol HCl	Betaxolol is a β₁ adrenergic receptor blocker with IC50 of 6 μM.	Selective	β1-adrenergic receptor, IC50: 6 μM
S4277	Bambuterol HCl	Bambuterol HCl is a potent β-adrenoceptor agonist, used in the treatment of asthma.	Selective
S4010	Acebutolol HCl	Acebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias.	Selective
S4135	Clorprenaline HCl	Clorprenaline HCl is a β2-receptor agonist, it has a significant expansion of the bronchial effect.	Selective
S1206	Bisoprolol fumarate	Bisoprolol fumarate is a selective type β1 adrenergic receptor blocker.	Selective
S2566	Isoprenaline HCl	Isoprenaline is a non-selective beta-adrenergic receptor agonist, used for the treatment of bradycardia and heart block.	Selective
S2509	Sotalol	Sotalol is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 μM.	Selective
S4100	Esmolol HCl	Esmolol is a cardioselective b-blocker, used to control rapid heartbeats or abnormal heart rhythms.	Selective
S4278	Carteolol HCl	Carteolol HCl is a β-adrenoceptor antagonist, used for the treatment of glaucoma.	Selective
S2091	Betaxolol	Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.	Selective
S4296	Salmeterol Xinafoate	Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms.	Selective
S2020	Formoterol Hemifumarate	Formoterol Hemifumarate is a potent, selective and long-acting β2-adrenoceptor agonist to β2 and β1 receptors with pKd of 8.12 and 5.58, respectively.	Selective
S2533	Ritodrine HCl	Ritodrine HCl is a hydrochloride salt of ritodrine which is a β-2 adrenergic receptor agonist.	Selective
S1856	Metoprolol Tartrate	Metoprolol Tartrate is a cardioselective β-adrenergic receptor blocker with IC50 of 42 ng/mL.	Selective
S2691	BMY 7378	BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pK_i of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pK_i of 8.3.	Pan	β2-adrenoceptor, pIC50: <5.0; β1-adrenoceptor, pIC50: 5.1
S2521	Epinephrine Bitartrate	Epinephrine Bitartrate is an alpha- and beta-adrenergic receptor stimulator.	Pan
S4291	Labetalol HCl	Labetalol HCl is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure.	Pan
S1831	Carvedilol	Carvedilol is a non-selective beta blocker/alpha-1 blocker with an IC50 of 3.8 μM for inhibition of LDL oxidation.	Pan

β-adrenergic receptor-Selectief Inhibitors | Agonists | Antagonists