MAO-A-Selectief Inhibitors
- MAO-A
- MAO-B
| Cat.nr. | Productnaam | Informatie | Selectief / Pan | IC50 / Ki |
|---|---|---|---|---|
| S3212 | Moclobemide (Ro 111163) | Moclobemide is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM. | Selective | MAO-A (5-HT), IC50: 6.1 μM |
| S2102 | Rasagiline Mesylate | Rasagiline Mesylate is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease. | Pan | MAO-A, IC50: 412 nM |
| S2339 | Paeonol | Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 μM. | Pan | MAO-A, IC50: 54.6 μM |
| S1472 | Safinamide Mesylate | Safinamide Mesylate is mesylate salt of Safinamide, selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A. Phase 3. | Pan | MAO-A, IC50: 580 μM |
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